Goljan Lectures Download
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Goljan Pathology Lecture Notes PDF Free Download Section. Now, in this section of the article, you will be able to get access to the Goljan Pathology Lecture Notes PDF Free Download file in.pdf format. The Goljan Pathology Lecture Notes PDF Free Download file has been uploaded to an online repository for the safer downloading. File Size: 1.26 MB. Apr 27, 2014 If nothing else, he helps you develop good instincts so you can 'play odds' better. If you can't get through all of his lectures, definitely do nutrition, heme/onc, and MSK/derm. The fact that Goljan audio is falling out of favor just makes it all the more valuable IMO. Mar 21, 2019 Features of the (Download Goljan RAPID REVIEW PATHOLOGY FIFTH EDITION pdf):: Many new high-yield, integrated margin notes and numerous summary tables for more efficient studying and understanding of disease processes. Updated content based on Dr. Goljan’s feedback from educators and medical students.
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Today we will share stuff related to Medical Audios. We will share Goljan Pathology Audio Lectures (Complete Lectures). Links to Download Audio Lectures are given bellow.
Content sample from Audio Lectures:
“1. Most imp: have to go into anaerobic glycolysis; end product is lactic acid (pyruvate is converted to lactate b/c of increased NADH); need to make NAD, so that the NAD can feedback into the glycolytic cycle to make 2 more ATP. Why do we have to use anaerobic glycolysis with tissue hypoxia? Mitochondria are the one that makes ATP; however, with anaerobic glycolysis, you make 2 ATP without going into the mitochondria. Every cell (including RBC’s) in the body is capable of
performing anaerobic glycolysis, therefore surviving on 2 ATP per glucose if you have tissue hypoxia. Mitochondrial system is totally shut down (no O2 at the end of the electron transport system – can only get 2 ATP with anaerobic glycolysis). Good news – get 2 ATP Bad news – build up of lactic acid in the cell and outside the cell (increased anion-gap metabolic acidosis with tissue hypoxia) due to lactic acidosis from anaerobic glycolysis. However, causes havoc inside the cell b/c increase of acid within a cell will denature proteins (with structural proteins messed up, the configuration will be altered); enzymes will be denatured, too. As a result, cells cannot autodigest anymore b/c enzymes are destroyed b/c buildup of acid. Tissue hypoxia will therefore lead to COAGULATION necrosis (aka infarction). Therefore, buildup of lactic acid within the cell will lead to Coagulation necrosis.
2. 2nd problem of lacking ATP: all ATP pumps are screwed up b/c they run on ATP. ATP is the power, used by muscles, the pump, anything that needs energy needs ATP. Na/K pump – blocked by digitalis to allow Na to go into cardiac muscle, so Ca channels open to increase force of contraction (therefore, sometimes you want the pump blocked), and sometimes you want to enhance it.
With no ATP, Na into the cell and it brings H20, which leads to cellular swelling (which is reversible). Therefore, with tissue hypoxia there will be swelling of the cell due to decreased ATP (therefore will get O2 back, and will pump it out – therefore it is REVERSABLE).
In true RBC, anaerobic glycolysis is the main energy source b/c they do not have mitochondria; not normal in other tissues (want to utilize FA’s, TCA, etc)”
Download Goljan Pathology Audio Lectures (Complete Lectures):
Link Goljan Pathology Transcript: Server 1 – Server 2
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Goljan Video Lectures
Cardiology: Link here
Cell injury: Link here
CNS-special senses: Link here
Endocrine: Link here
Fluid_Hemodynamic: Link here
Gastrointestinal: Link here
OB-Gyn: Link here
Hepatobiliary-pancrease: Link here
Inflammation: Link here
Muscoloskeletal: Link here
Nutrition_Neoplasia_Hematology: Link here
Renal: Link here
Respiratory: Link here
Skin: Link here
Goljan Pathology Lectures
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